Yves Mély

Yves Mély is professor of biophysics at the Faculty of Pharmacy at University of Strasbourg. Pharmacist (graduated in 1984) and holder of a PhD in biophysics from the Louis Pasteur University in Strasbourg (1988), he was appointed lecturer in 1989, then full professor in 1998. He heads the team "Biophotonics of molecular and cellular interactions ”since 1999 and the Bioimaging and Pathologies laboratory (UMR 7213 then UMR 7021) since 2009. His research activity can be divided into two research axes. The first relates to the development of fluorescence techniques (quantitative and high resolution microscopy) and innovative fluorescence probes for membranes, proteins and nucleic acids. The second axis deals with the application of these techniques and probes to characterize the properties and functions of HIV-1 virus proteins (notably the nucleocapsid protein) as well as those of proteins involved in epigenetic regulation (UHRF1 and DNMT1 proteins) and more recently of proteins from Pseudomonas aeruginosa. In addition to understand the molecular mechanisms and functions of these proteins in interaction with their ligands, his research aims to discover new therapeutic avenues. Professor Mély has published more than 300 scientific articles. He is the chair of the international conference series "Methods and Applications in Fluorescence" since 2011 and the co-chair of the conference series "Fluorescent Biomolecules and their Building Blocks: Design and Applications (FB3)" since 2014. He also co-founded the journal "Methods and Applications in Fluorescence" and is one of its editors since 2012.

He has obtained an Adrerus thesis prize in 1990 and a von Humboldt fellowship for a sabbatical at the Max Planck Institute of Biophysics, Frankfurt in 1997. He has been invited as "Senior Scientist" at Riken, Tokyo, in 2015. He received the award “Gregorio Weber Award for Excellence in Fluorescence Theory and Applications” in 2017. He was appointed Doctor Honoris Causa at Taras Shevchenko University in Kiev and senior member of the Institut Universitaire de France in 2018.